Marketing mix para las empresas exportadoras de palta Hass en la provincia de Barranca, año 2019

Para el presente trabajo, se dio a conocer como objetivo principal analizar las estrategias de Marketing Mix Para Las Empresas Exportadoras De Palta Hass En La Provincia De Barranca, Año 2019, una vez dado esta información en segundo momento de investigación, se emprenderá los objetivos específicos que consisten en analizar las estrategias de producto, precio, plaza y promoción que se aplicaron en las empresas exportadoras de palta hass en barranca. Para analizar los datos se realizó una encuesta teniendo como instrumento el cuestionario, cuyos resultados se procesaron a través del programa SPSS, del cual se obtuvieron tablas estadísticas y gráficos de barras que se usara para poder describir los datos estadísticos univariable de la variable marketing mix. Por último se deduce que el marketing mix para la exportación de palta hass en la provincia de barranca tiene una tendencia positiva, ya que ayudara a las empresas a que sus exportaciones mejor en cuanto a su calidad, promoción distribución y su producto sean mejores, por lo mismo es necesario potenciar la estrategia marketing mix de parte de los productores, llenándose de conocimientos y capacitación para que crezcan como mercado y obtengan el liderazgo frente a sus competidores. Se aplicó un método de investigación cuantitativo de tipo descriptiva de diseño no experimental, trasversal y se utilizaran una técnica de encuestas para obtener la información atreves de un cuestionario estructurado y validado

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field